You've successfully added to your alerts. And although rosuvastatin … Endocrine. Usefulness of aggressive lipid-lowering therapy with rosuvastatin in hypercholesterolemic patients with concomitant type 2 diabetes. Malays Fam Physician. The mechanism of action of both atorvastatin and rosuvastatin (called statins) is identical. aLDL = low-density-lipoprotein, ATP III = Adult Treatment Panel III. dChange divided by the preindex LDL cholesterol value. Please enter a Recipient Address and/or check the Send me a copy checkbox. However the usual dose of atorvastatin is 10mg … Systematic Review Using Data from 1.9 Million Patients. 2010 Mar;25(1):27-35. doi: 10.3904/kjim.2010.25.1.27. Int J Endocrinol. Currently, the most commonly used agents for lowering LDL cholesterol levels are hydroxymethylglutarase-coenzyme A reductase inhibitors, or statins. Lipitor ® (atorvastatin calcium) and Crestor ® (rosuvastatin calcium) are both cholesterol medications.  |  Burnout Might Really Be Depression; How Do Doctors Cope? [4] published additional therapeutic options and more aggressive LDL cholesterol goals for patients with multiple cardiovascular risks. bIndependent sample t test used for comparison of means. Study 1; Based on findings, atorvastatin and rosuvastatin are equally as safe and effective in lowering cholesterol and possibly reversing plaque build-up with aggressive treatment. HHS Kameda A, Nakamura A, Kondo Y, Kimura M, Terauchi Y. Diabetol Int. eAdjusted for age, sex, baseline laboratory values, duration of therapy, and National Cholesterol Education Program risk status. No significant differences were found in HDL cholesterol and triglyceride levels between groups. b n denotes number of patients not at goal at baseline. Methods and results: NLM Effects of switching to low-dose rosuvastatin (5 mg/day) on glucose metabolism and lipid profiles in Japanese patients with type 2 diabetes and dyslipidemia: a single-arm, prospective, interventional trial. Michael F. Bullano; Siddhesh Kamat; Debra A. Wertz; Gerald M. Borok; Sanjay K. Gandhi; Kenneth L. McDonough; Vincent J. Willey. You will receive email when new content is published. 2017 Apr 30;12(1):39-40. eCollection 2017. aLDL = low-density-lipoprotein. Methods: Electronic medical and pharmacy administrative claims from a western U.S. health plan with approximately 8 million covered members were extracted and used in this retrospective, longitudinal cohort study. Statins in hypercholesterolaemia: a dose-specific meta-analysis of lipid changes in randomised, double blind trials. Please see our, 2001 2020 Mar;35(2):342-350. doi: 10.3904/kjim.2018.272. Ischemic Stroke May Hint at Underlying Cancer, Topol: US Betrays Healthcare Workers in Coronavirus Disaster, The 6 Dietary Tips Patients Need to Hear From Their Clinicians, Moderate (≥2 risk factors [10-yr risk, <10%]), Moderately high (≥2 risk factors [10-yr risk, 10-20%]), High (CHD or CHD risk equivalent [10-yr risk, >20%]), Very high (CVD + DM, ACS, or MS [10-yr risk, >20%]), Mean ± S.D. They are quite similar in many aspects; however, there are a few important differences between the … In response to results from recent clinical trials, Grundy et al. postindex concentration (mg/dL). Get the latest research from NIH: cInsufficient sample size to detect statistically significant differences (power = 39%) in goal attainment across statin groups (p = 0.088). 2008 Dec;15(6):314-23. doi: 10.5551/jat.e567. Since cholesterol synthesis peaks between midnight and 2 am, simvastatin, pravastatin, fluvastatin, and pitavastatin have a shorter half-life and should be taken at bedtime. Endocrinological Features of Hartsfield Syndrome in an Adult Patient With a Novel Mutation of FGFR1, The Effect of Sprint Interval Training on Body Composition of Postmenopausal Women, Hypothalamic–Pituitary and Growth Disorders in Survivors of Childhood Cancer, Advances in Allergen Immunotherapy for Asthma, Remote, Non-Physician-Led Care Cuts LDL, BP in High-Risk Patients, Statins Beneficial in Elderly, Guidelines Should Be Strengthened, AACE Issues 'Cookbook' Algorithm to Manage Dyslipidemia, First-of-Its Kind Guideline on Lipid Monitoring in Endocrine Diseases, Women With Heterozygous FH Less Likely to Receive Treatment, Amazon Launches Online Pharmacy in New Contest With Drug Retail, Pharmacotherapy Considerations in Hospitalized Patients With COVID-19 Pneumonia. Please check this other discussion --- 2nd URL Commenting is limited to medical professionals.